I analysed the 2nd death stranding trailer. I can say where it (probably) takes place: In France, Saint Malo. Here is why:
1st - look at the power poles in the trailer and on my researched photos. They both look kinda same. The photo with the soldiers on the left walking up the street has a power pole on the right background which looks identical with the one in the trailer.
2nd - Saint Malo's history fits in the trailer's scenario. It was the stronghold of the Germans in WW2. In the Trailer a radio speaks german (when del Toro looks up) saying "Nach den Richtlinien der Notregelung folgt nun, wie wir es für richtig halten. Dass heißt, alle die nun über weiteres... " meaning "According to the guidelines of the emergency regulation now follows, as we consider it is right. This means, everyone who..." Another story fact is, that Saint Malo was bombed and over 90% of it was destroyed. Same as in the trailer.
https://youtu.be/3oXjCw9UqJg
3rd - The coastline, the chimney and the buildings looks all same. The town is above its coast. The wall around it has entraces, in real and in the trailer. The town is near the ocean.